Conclusions
The behavior of 5(6)-hydroxybenzimidazole in aminomethylation was studied. 4,6-Bissubstituted Mannich bases were obtained for the first time by selection of the conditions and reagents.
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L. D. Smirnov and K. M. Dyumaev, Khim.-Farm. Zh., No. 4, 28 (1982).
E. K. Cole and G. Crauk, J. Agr. Food Chem.,22, 918 (1974).
M. Ewert and H. Oelschläger, Arch. Pharm.,308, No. 7, 550 (1975).
A. F. Pozharskii, Khim. Geterotsikl. Soedin., 723 (1977).
R. S. Varma and A. Kapoor, Eur. J. Med. Chem. Chim. Therapeutica,15, No. 6, 536 (1980).
L. D. Smirnov, Yu. V. Kuznetsov, L. M. Apasheva, K. D. Poltorak, A. L. Grinchenko, K. M. Dyumaev, and N. M. Émanuél, Inventor's Certificate No. 1098934 (USSR); Byull. Izobret., No. 23 (1984).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, pp. 1855–1858, August, 1985.
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Smirnov, L.D., Kuznetsov, Y.V., Stolyarova, L.G. et al. Aminomethylation of 5(6)-hydroxybenzimidazole. Russ Chem Bull 34, 1705–1708 (1985). https://doi.org/10.1007/BF00948521
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DOI: https://doi.org/10.1007/BF00948521