Conclusions
A method was proposed for the preparation of N-trichloroacetoxyphthalimide, a new efficient reagent for the synthesis of the N-hydroxyphthalimide esters of N-protected amino acids, which consists in treating N-hydroxyphthalimide with CCl3COCl.
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Literature cited
G. W. Anderson, J. E. Zimmermann, and F. M. Callahan, J. Am. Chem. Soc.,86, 1839 (1964).
G. H. L. Nefkens and G. I. Tesser, J. Am. Chem. Soc.,83, 1263 (1961).
O. A. Kaurov, V. F. Martynov, and V. B. Morozov, Zh. Obshch. Khim.,40, 908 (1970).
G. H. L. Nefkens, G. I. Tesser, and R. I. F. Nivard, Rec. Trav. Chim.,81, 683 (1962).
E. Grochowski and J. Jurczak, Synthesis, 277 (1977).
S. Sakakibara and N. Inukai, Bull. Chem., Soc. Jpn.,38, 1979 (1965).
V. H. Gross and I. Keitel, J. Prakt. Chem.,311, 692 (1969).
A. N. Kost (ed.), General Practical Guide in Organic Chemistry [Russian translation], Mir, Moscow (1965).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 943–945, April, 1984.
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Il'ina, A.V., Davidovich, Y.A. & Rogozhin, S.V. N-trichloroacetoxyphthalimide as a new reagent for the synthesis of the N-hydroxyphthalimide esters of N-protected amino acids. Russ Chem Bull 33, 869–871 (1984). https://doi.org/10.1007/BF00947860
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DOI: https://doi.org/10.1007/BF00947860