Chemistry of Heterocyclic Compounds

, Volume 5, Issue 2, pp 212–214 | Cite as

Vapor-phase catalytic oxidation of aβ-picoline fraction

  • L. Ya. Leitis
  • M. V. Shimanskaya
Article
  • 21 Downloads

Abstract

The vapor-phase catalytic oxidation with atmospheric oxidation of a β-picoline fraction consisting of a mixture of 3- and 4-methylpyridines and 2,6-lutidine containing small amounts of 2-methylpyridine and pyridine has been studied. On a vanadium oxide catalyst at 440° C with a contact time of 1.2 sec and a molar ratio of oxygen to steam to methylpyridine of 7 ∶ 54 ∶ 1, a high degree of conversion of the 4-methylpyridine and the 2,6-lutidine into pyridine-4-aldehyde and 6-methylpyridine-2-aldehyde, respectively, has been achieved. The main component of the aqueous solution of the catalyzate (after the isolation of thepyridine aldehydes in the form of oximes) is 3-methylpyridine.

Keywords

Oxidation Oxygen Aqueous Solution Steam Organic Chemistry 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    L. Ya. Leitis and M. V. Shimanskaya, KhGS [Chemistry of Heterocyclic Compounds],3, 507, 1967.Google Scholar
  2. 2.
    I. M. Polyakova, ZhPKh,20, 845, 1947.Google Scholar
  3. 3.
    E. A. Spähr and L Spitzer, Ber.,59, 1477, 1926.Google Scholar
  4. 4.
    M. Leve and I. Pesheva, Farmatsiya, 1, 266, 1965.Google Scholar
  5. 5.
    M. V. Shimanskaya and S. A. Hiller, The Chemistry, Technology, and Uses of Pyridine and Quinoline Derivatives [in Russian], Riga, p. 185, 1960.Google Scholar
  6. 6.
    E. E. Paulane, A. A. Avot, M. V. Shimanskaya, V. A. Slavinskaya, and D. P. Kikust, Izv. AN LatvSSR, ser. khim., 21, 1966.Google Scholar
  7. 7.
    S. Ginsburg and I. Wilson, J. Am. Chem. Soc.,79, 481, 1957Google Scholar

Copyright information

© Consultants Bureau 1972

Authors and Affiliations

  • L. Ya. Leitis
    • 1
  • M. V. Shimanskaya
    • 1
  1. 1.Institute of Organic Synthesis AS Latvian SSRRiga

Personalised recommendations