Summary
Eight well-trained males were studied before, during and after 6 months of a progressively increased amount of endurance training in order to elucidate the effects on the apoproteins and apo-lipoproteins. Initially high HDL-cholesterol levels were revealed (1.62±0.15 mmol×l−1, mean ± SE.). After a transient but not significant, slight decline at the onset of the increased training program (1.57±0.06 mmol×l−1) HDL-cholesterol increased gradually to the end of the training period (1.92±0.12 mmol×l−1). There was an increased aerobic capacity as judged by maximal oxygen uptake and by lactate concentration during standardized submaximal work. However, at the end of the training period, a levelling off in maximal oxygen uptake was revealed, while HDL-cholesterol was still increasing. The present data demonstrate that HDL can be influenced by training at all levels of aerobic capacity.
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References
Andersen P (1975) Capillary density in skeletal muscle of man. Acta Physiol Scand 95: 203–205
Andersen P, Henriksson J (1977) Capillary supply of the quadriceps femoris muscle of man: Adaptive response to exercise. J Physiol 270: 677–691
Burnstein M, Samaille J (1960) Sur un dosage rapide du cholesterol lie aux α-etΒ-lipoproteines du serum. Clin Chim Acta 5: 609
Dufaux B, Schmit G, Assmann G, Hollmann W (1982) Plasma lipoproteins and physical activity. Int J Sports Med 3: 58–60
Farrell PA, Barboriak J (1980) The time course of alterations in plasma lipid and lipoprotein concentrations during eight weeks of endurance training. Atherosclerosis 37: 231–238
Goldstein HL, Brown SB (1977) The low density lipoprotein pathway and its relation to atherosclerosis. Ann Rev Biochem 46: 897–930
Green PHR, Glickman (1981) Intestinal lipoprotein metabolism. J Lipid Res 22: 1153–1173
Havekes L, Hemmik J, de Wit E (1982) Low density lipoprotein apoprotein B in plasma as measured by radial immunodiffusion and rocket immuno electrophoresis. Clin Chem 27: 1829–1833
Havel RJ, Eder HA, Bragdon JH (1955) The determination and chemical composition of ultra-centrifugally separated lipoproteins in human serum. J CLin Invest 34: 1345–1353
Kiens B, JØrgensen I, Lewis S, Jensen G, Lithell H, Vessby B, Hoe S, Schnohr P (1980) Increased plasma HDL-cholesterol and apo A-I in sedentary middle-aged men after physical conditioning. Eur J Clin Invest 10: 203–209
Kiens B, Gad P, Lithell H, Vessby B (1981a) Minor dietary effects on HDL in physically active men. Eur J Clin Invest 11: 265–271
Kiens B, Gad P, éssen B, Lithell H (1981b) HDL-cholesterol and apo A-I concentration in conditioned middle-age men with long-term alteration in fat intake and with de-training. Med v Sports Exercise 13: 106
Kuusi T, Kinnunen PKJ, NikkilÄ EA (1979) Hepatic endothelial lipase antiserum influences rat plasma low and high density lipoproteins in vivo. FEBS Lett 104: 384–388
Kuusi T, NikkilÄ EA, Saarinen P, Varjo P, Laitinen LA (1982) Plasma high density lipoproteins HDL2, HDL3 and postheparin plasma lipases in relation to parameters of physical fitness. Atherosclerosis 41: 209–219
Lithell H, LindgÄrde F, Hellsing K, Lundqvist G, Nygaard E, Vessby B, Saltin B (1981) Body weight, skeletal muscle morphology and enzyme activities in relation to fasting serum insulin concentration and glucose tolerance in 48-year-old men. Diabetes 30: 19–25
Lowry OH, Passoneau JV (1973) A flexible system of enzymatic analysis. Academic Press New York
Nikkilā EA, Taskinen M-R, Rehunen S, HÄrkönen M (1978) Lipoprotein lipase activity in adipose tissue and skeletal muscle of runners: Relation to serum lipoproteins. Metabolism 27: 1661–1670
Peltonen P, Marniemi J, Hietanen E, Vouri I, Ehnholm C (1981) Changes in serum lipids, lipoproteins and heparin releasable lipolytic enzymes during moderate physical training in man: A longitudinal study. Metabolism 30: 518–526
Rush RL, Leon L, Turrel J (1971) Automated simultaneous cholesterol and triglyceride determination on the auto analyzer II instrument. Advances in automated analysis, Thurman Associates 1: 503–507
Svedenhag J, Lithell H, Juhlin-Dannfelt A, Henriksson H (1983) Increase in skeletal muscle lipoprotein lipase following endurance training in man. Atherosclerosis 49: 203–207
Vessby B, Boberg J, Gustafsson I-B, Karlström B, Lithell H, östlund-Lindqvist A-M (1980) Reduction of high-density lipoprotein cholesterol and apolipoprotein A-I concentrations by a lipid lowering diet. Atherosclerosis 35: 21–27
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Kiens, B., Lithell, H. & Vessby, B. Further increase in high density lipoprotein in trained males after enhanced training. Europ. J. Appl. Physiol. 52, 426–430 (1984). https://doi.org/10.1007/BF00943374
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DOI: https://doi.org/10.1007/BF00943374