Abstract
We present herein the case of a 74-year-old woman found to have a pleomorphic adenoma, or so-called mixed tumor, of the breast. The patient presented with a hard mass, 3 cm in diameter, located just beneath the left areola. Physical examination suggested a diagnosis of breast carcinoma; however, the findings of both ultrasonography and mammography indicated a benign neoplasm. Aspiration biopsy cytology was evaluated as class III and the diagnosis of pleomorphic adenoma was finally confirmed by examination of an excisional biopsy specimen. As it is a rare benign tumor, pleomorphic adenoma of the breast has been mistaken for a malignant tumor clinically, mammographically, cytologically, and even by frozen section. Thus, an awareness of this disease in the breast will help to prevent misdiagnosis and overaggressive surgery.
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References
Haagensen CD (1986) Diseases of the breast, 3rd edn. Saunders, Philadelphia, pp 350–356
Austin JR, Crockett DM (1992) Pleomorphic adenoma of the palate in a child. Head Neck 14:58–61
Leunig A, Grevers G (1994) Pleomorphes Adenom der Kieferhöhle. Laryngorhinootologie 73:595–596
Couloigner V, Julien N, Molas G, Sterkers O (1993) Adénome pléomorphe de la cloison nasale. À propos d'un cas. Ann Otolaryngol Chir Cervicofa 110:230–233
Zakzouk MS (1985) Pleomorphic adenoma of the larynx. J Laryngol Otol 99:611–616
Sun CF, Wang YL, Xu LT, Wu LH (1985) Primary low malignancy tracheobronchial tumor. Chin Med J (Engl) 98:203–205
Moran CA (1995) Primary salivary gland-type tumors of the lung. Semin Diagn Pathol 12:106–122
Tsunoda S, Yabuno T, Sakaki T, Morimoto T, Hoshida T, Hirabayashi H, Tsuzuki T (1994) Pleomorphic adenoma of the lacrimal gland manifesting as exophthalmos in adolescence — case report. Neurol Med Chir 34:814–816
Ballance WA, Ro JY, El-Naggar AK, Grignon DJ, Ayala AG, Romsdahl MG (1990) Pleomorphic adenoma (benign mixed tumor) of the breast: an immunohistochemical, flow cytometric, and ultrastructural study and review of the literature. Am J Clin Pathol 93:795–801
Moran CA, Suster S, Carter D (1990) Benign mixed tumors (pleomorphic adenomas) of the breast. Am J Surg Pathol 14: 913–921
Chen KTK (1990) Pleomorphic adenoma of the breast. Am J Clin Pathol 93:792–794
Betta PG, Spinoglio G (1992) Benign mixed salivary-type tumor of the breast. Eur J Surg Oncol 18:304–306
Simha MR, Doctor VM, Udwadia TE (1992) Mixed tumor of salivary gland type of the male breast. Ind J Cancer 29:14–17
Kanter MH, Sedeghi M (1993) Pleomorphic adenoma of the breast: cytology of fine-needle aspiration and its differential diagnosis. Diagn Cytopathol 9:555–558
Tsubura A, Inui T, Senzaki H, Morii S, Koji T, Hatano T, Yamamoto M (1988) An operative case of pleomorphic adenoma of the breast (in Japanese). Nyugan no Rinsho (Jpn J Breast Cancer) 3:590–594
Ando T, Endo K, Hirai T, Makita F, Ohtaki A, Iino Y, Morishita Y, Nakajima T (1994) Pleomorphic adenoma of male mammary gland (in Japanese with English abstract). Nyugan no Rinsho (Jpn J Breast Cancer) 9:359–362
Lecene AL (1906) Observation d'un cas de tumeur “mixte” du sein. Rev Chir 33:434
Van der Walt JD, Rohlova B (1982) Pleomorphic adenoma of the human breast. A report of a benign tumor closely mimicking a carcinoma clinically. Clin Oncol 8:361–365
Sheth MT, Hathway D, Petrelli M (1978) Pleomorphic adenoma (“mixed” tumor) of human female breast mimicking carcinoma clinico-radiologically. Cancer 41:659–665
Witten R, Uvelius B, Cameron R (1986) Pleomorphic adenoma in the breast of a human female. Aspiration biopsy findings and receptor determinations. Case report. Acta Chir Scand 152:709–713
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Mochinaga, N., Yatsugi, T., Tomokawa, S. et al. Pleomorphic adenoma of the breast: Report of a case. Surg Today 27, 278–281 (1997). https://doi.org/10.1007/BF00941663
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DOI: https://doi.org/10.1007/BF00941663