Parasitology Research

, Volume 79, Issue 3, pp 235–239 | Cite as

Kinetic model of parasite development and of the host microelement content under combined drug treatment

  • A. Damyanova
  • S. Teodorova
  • M. Gabrashanska
Original Investigations


The content of nine microelements has been investigated in a parasite—host system by nondestructive neutron activation analysis. A mathematical model has been proposed for the development ofAscaridia galli in the “Leghorn” chocks intestines and for the microelement content dynamics under combined treatment with antiparasite agent and microelements. An analytical solution of the system of nonlinear differential equations has been obtained for the case of simple invasion. The model explains well the experimentally observed process of the change in the microelement content. The recovery constant has been introduced for the damaged by the helminthosis tissue and its value has been determined.


Differential Equation Mathematical Model Drug Treatment Kinetic Model Activation Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bell D, Freemann B (1971) Physiology and biochemistry of the domestic fowl, vol 1. Academic Press, London New YorkGoogle Scholar
  2. Damyanova A, Gabrashanska M (1988) Mineral content of helminths and its hosts. I.Fasciola hepatica and tissues ofBos taurus. Helminthologia 25:1–8Google Scholar
  3. Enigk K, Feder H, Dey-Hazra A (1973) Zur chemischen Zusammensetzung vonAscaris suum (Nematoda) nach unterschiedlicher Mineralstoffütterung der Wirtstiere. Z Parasitenkd 42:147–164PubMedGoogle Scholar
  4. Gabrashanska M, Kanev I, Damyanova A, Nachinzova V (1989) Mineral content of helminths and tissues of their hosts. Helminthology (Bulg Acad Sci) 27:5–8Google Scholar
  5. Greichus A, Greichus I (1980) Identification and quantification of some elements in the hog round wormsAscaris lumbricoides suum and some certain tissues of its hosts. Int J Parasitol 10:89–91PubMedGoogle Scholar
  6. Sadikova-Samarina I (1956) Spectral, chemical investigation ofAscaridia galli, Fasciola hepatica. Ascaris suum and tissues of infected and noninfected hosts. Proc Sci Conf VOG M 4:235–246Google Scholar
  7. Slysarev A (1975) Some aspects of mineral metabolism of helminths. Parasitology Probl 2:156–158Google Scholar
  8. Ynce Y (1976) Some elements and their relationships toAscaris suum. Int J Parasitol 6:127–128PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • A. Damyanova
    • 1
  • S. Teodorova
    • 1
  • M. Gabrashanska
    • 2
  1. 1.Institute of Nuclear Research and Nuclear EnergyBulgarian Academy of SciencesSofiaBulgaria
  2. 2.Central Laboratory for HelminthologyBulgarian Academy of SciencesSofiaBulgaria

Personalised recommendations