Archives of Gynecology and Obstetrics

, Volume 241, Issue 1, pp 33–35 | Cite as

Insulin-like growth factor-binding protein PP12 in ovarian cyst fluid

  • M. Seppälä
  • G. Than


Elevated levels of insulin-like growth factor-binding protein (IGF-bp) were recently found in the serum of patients with ovarian tumors. We studied the concentration of IGF-bp in cyst fluids of 37 women operated on for benign or malignant ovarian cysts. The levels were elevated (>47 μg/l) in 6 of 28 benign, but in none of the nine malignant ovarian cysts. The highest IGF-bp concentration (447 μg/l) was observed in a benign serous cystadenoma.

Key words

IGF-binding protein Placental protein 12 Ovarian tumors 


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. Seppälä
    • 1
  • G. Than
    • 2
  1. 1.Department I of Obstetrics and GynecologyHelsinki University Central HospitalHelsinkiFinland
  2. 2.Department of Obstetrics and GynecologyUniversity of PécsPécsHungary

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