Archives of Gynecology and Obstetrics

, Volume 241, Issue 2, pp 121–126 | Cite as

The significance of female sex steroids on the vascular permeability of the traumatised uterine serosa of rats

  • M. A. Gouveia
  • H. W. Halbe
  • N. Schutze Filho


Using experiments with conjugated hormones, and their influence on vascular permeability assessed by the colloidal carbon technique, we have investigated the effect of female sex steroids on the microcirculation of the uterine horn of virgin rats. We found that oestrogen inhibited vascular permeability in inflammatory conditions. Progesterone increased vascular permeability.

Key words

Vascular permeability Uterus Oestrogen Progesterone 


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. A. Gouveia
    • 1
  • H. W. Halbe
    • 2
  • N. Schutze Filho
    • 3
  1. 1.Laboratory of Experimental Pathology, Faculty of MedicineUniversity of São PauloSão PauloBrazil
  2. 2.Department of Obstetrics and Gynecology, Faculty of MedicineUniversity of São PauloSão PauloBrazil
  3. 3.Laboratory of Experimental Surgery, Faculty of MedicineUniversity of São PauloSão PauloBrazil

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