Zeitschrift für Parasitenkunde

, Volume 72, Issue 2, pp 213–220 | Cite as

IgE response inStrongyloides ratti-infected rats with special reference to the life cycle of the parasite

  • M. Korenaga
  • Y. Nawa
  • I. Tada
Original Investigations

Abstract

Parasite-specific IgE antibody response was examined inStrongyloides ratti-infected rats. The results showed that the parasite-specific IgE antibody response was generated after a primary infection. However, repeated infections rather depressed the level of parasite-specific IgE antibody in the serum. Immunization limited to specific stages of the parasite revealed that stimulation of parasite-specific IgE antibody was related to the intestinal adult stage. On the other hand, depression of IgE titers was related to the tissue-migrating larval stage. The capacity of the each stage of the parasite to induce specific IgE response may be related to the variable results of the IgE responses in human strongyloidiasis.

Keywords

Life Cycle Variable Result Antibody Response Special Reference Larval Stage 

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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • M. Korenaga
    • 1
  • Y. Nawa
    • 2
  • I. Tada
    • 1
  1. 1.Department of Parasitic DiseasesKumamoto University Medical SchoolKumamotoJapan
  2. 2.Department of AnatomyKumamoto University Medical SchoolKumamotoJapan

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