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Hatching ofSchistosoma mansoni eggs is a Ca2+/calmodulin-dependent process

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Abstract

The effect of calcium channel blockers (diltiazem and verapamil) and a calmodulin antagonist (W-7) on the hatching ofSchistosoma mansoni eggs in fresh water was studied. The hatching of the eggs was inhibited by diltiazem and W-7 in a dose-dependent fashion and only slightly by verapamil. The present study indicates that the hatching ofS. mansoni eggs is a Ca2+/calmodulindependent process.

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Authors and Affiliations

  1. Second Department of Internal Medicine, Nagasaki University School of Medicine, Sakamotomachi, 852, Nagasaki, Japan

    Tatsuya Katsumata, Shigeru Kohno, Keizo Yamaguchi & Kohei Hara

  2. Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, 852, Nagasaki, Japan

    Yoshiki Aoki

Authors
  1. Tatsuya Katsumata
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  2. Shigeru Kohno
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  3. Keizo Yamaguchi
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  4. Kohei Hara
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  5. Yoshiki Aoki
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Katsumata, T., Kohno, S., Yamaguchi, K. et al. Hatching ofSchistosoma mansoni eggs is a Ca2+/calmodulin-dependent process. Parasitol Res 76, 90–91 (1989). https://doi.org/10.1007/BF00931079

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  • DOI: https://doi.org/10.1007/BF00931079

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