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Structure and possible function ofPlasmodium falciparum proteins exported to the erythrocyte membrane

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Abstract

On infecting the red blood cell, the malaria parasitePlasmodium falciparum induces alterations in the erythrocyte membrane. The parasite appears to synthesize proteins that are exported across the parasitophorous vacuole membrane and through a system of membraneous structures within the cytoplasm of the host cell to the surface membrane of the erythrocyte. There, these proteins are either released or remain associated with the membrane. In this review we describe the structure and discuss the possible functions of some of the exported proteins.

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Authors and Affiliations

  1. Department of Microbiology, Behringwerke AG, W-3550, Marburg, Germany

    B. Knapp & E. Hundt

  2. Fraunhofer Institute for Toxicology and Aerosol Research, W-2000, Hamburg, Germany

    K. R. Lingelbach

Authors
  1. B. Knapp
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  2. E. Hundt
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  3. K. R. Lingelbach
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Dedicated to Prof. Dr. Eckert (Zürich) on the occasion of his 60th birthday

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Knapp, B., Hundt, E. & Lingelbach, K.R. Structure and possible function ofPlasmodium falciparum proteins exported to the erythrocyte membrane. Parasitol Res 77, 277–282 (1991). https://doi.org/10.1007/BF00930901

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  • DOI: https://doi.org/10.1007/BF00930901

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