Skip to main content
SpringerLink
Log in

The trypanosome surface glycoprotein procyclin is expressed only on tsetse fly vector stages of the parasite

  • Short Communications
  • Published:
Parasitology Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Black SJ, Jack RM, Morrison WI (1983) Host-parasite interactions which influence the virulence ofTrypanosome (trypanozoon) brucei brucei organisms. Acta Trop 40:11–18

    Google Scholar 

  • Black SJ, Sendashonga CN, O'Brien C, Borowy NK, Naessens M, Webster P, Murray M (1985) Regulation of parasitaemia in mice infected withTrypanosoma brucei. Curr Top Microbiol Immunol 117:93–118

    Google Scholar 

  • Brun R, Schonenberger M (1979) Cultivation andin vitro cloning of procyclic culture forms ofTrypanosoma brucei in a semi-defined medium. Acta Trop 36:289–292

    Google Scholar 

  • Brun R, Schoenberger M (1981) Stimulating effect of citrate and cis-aconitate on the transformation ofTrypanosoma brucei bloodstream forms to procyclic formsin vitro. Z Parasitenkd 66:17–24

    Google Scholar 

  • Czichos J, Nonnenggesser C, Overath P (1986)Trypanosoma brucei: cis-aconitate and temperature reduction as triggers of synchronous transformation of bloodstream to procyclic trypomastigotesin vitro. Exp Parasitol 62:283–291

    Google Scholar 

  • Jack RM, Black SJ, Reed SL, Davis CE (1984) Indomethacin promotes differentiation ofTrypanosoma brucei. Infect Immun 43:445–448

    Google Scholar 

  • Jennings FW, Urquhart GM (1985) Induction of human-sensitiveTrypanosoma brucei stabilates into human-resistant “T. rhodesiense”. Trans Roy Soc Trop Med Hyg 79:80–85

    Google Scholar 

  • Reed SL, Fierer AS, Goddard DR, Colmerauer MEM, Davis CE (1985) Effect of theophylline on differentiation ofTrypanosoma brucei. Infect Immun 49:844–847

    Google Scholar 

  • Richardson JP, Jenni L, Beecroft RL, Pearson TW (1986) Procyclic tsetse fly midgut forms and culture forms of African trypanosomes share stage-and species-specific surface antigens identified by monoclonal antibodies. J Immunol 136:2259–2264

    Google Scholar 

  • Richardson JP, Beecroft RP, Tolson DL, Liu MK, Pearson TW (1988) Procyclin: an unusual immunodominant glycoprotein surface antigen from the procyclic stage of African trypanosomes. Molec Biochem Parasitol 31:203–216

    Google Scholar 

  • Roditi I, Schwarz H, Pearson TW, Beecroft RP, Liu MK, Richardson JP, Buhring HJ, Pleiss J, Bulow R, Williams RO, Overath P (1989) Procyclin gene expression and loss of the variant surface glycoprotein during differentiation ofTrypanosoma brucei. J Cell Biol 108:737–746

    Google Scholar 

  • Sendashonga CN, Black SJ (1982) Humoral responses againstTrypanosoma brucei variable surface antigens are induced by degenerating parasites. Parasite Immunol 4:245–257

    Google Scholar 

  • Shapiro SZ, Naessens J, Leisegang B, Moloo SK, Magondu J (1984) Analysis by flow cytometry of DNA synthesis during the life cycle of African trypanosomes. Acta Trop 41:313–323

    Google Scholar 

  • Shapiro SZ (1986)Trypanosoma brucei: Release of variant surface glycoproteins during the parasite life cycle. Exp Parasitol 64:432–437

    Google Scholar 

  • Smith CJ, Levine RF, Mansfield JM (1982) Cloning of African trypanosomes in mice immunosuppressed by cyclophosphamide treatment. Am J Trop Med Hyg 31:1098–1102

    Google Scholar 

  • Vickerman K (1985) Development cycles and biology of pathogenic trypanosomes. Br Med Bull 41:105–114

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medical Center, University of California, San Diego, 225 Dickinson Street, 92103-9981, San Diego, CA, USA

    M. E. M. Colmerauer & C. E. Davis

  2. Department of Biochemistry and Microbiology, University of Victoria, V8W 2Y2, Victoria, British Columbia, Canada

    T. W. Pearson

Authors
  1. M. E. M. Colmerauer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. E. Davis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. W. Pearson
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Colmerauer, M.E.M., Davis, C.E. & Pearson, T.W. The trypanosome surface glycoprotein procyclin is expressed only on tsetse fly vector stages of the parasite. Parasitol Res 76, 171–173 (1989). https://doi.org/10.1007/BF00930841

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00930841

Keywords

Search

Navigation