International Ophthalmology

, Volume 18, Issue 6, pp 355–358 | Cite as

Full-thickness macular holes treated with vitrectomy and tissue glue

  • Maurits A. D. Tilanus
  • August F. Deutman


In the surgical treatment of full-thickness macular holes good results have been published with the combination of vitrectomy, gas and application of Transforming Growth Factorβ 2. Other authors report a 73% success rate in closing a full-thickness macular hole after vitrectomy and gas tamponade alone. We used, in addition to vitrectomy and gas tamponade, a tissue glue to stimulate adhesion of the elevated cuff of neurosensory retina surrounding a full-thickness macular hole and to close to hole itself. A total of 15 eyes of 13 patients (3 men, 10 women), with stage 3 and 4 macular holes were operated. All of the 13 uncomplicated cases showed complete closure of the macular hole. In one case (8%) the visual acuity decreased one line in spite of a funduscopically closed hole, and in two cases (16%) visual acuity remained the same despite closure. Increased visual acuity was seen in ten cases (76%), eight of which improved more than two lines.

Key words

macular hole vitrectomy tissue glue 


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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Maurits A. D. Tilanus
    • 1
  • August F. Deutman
    • 1
  1. 1.Institute of OphthalmologyUniversity Hospital NijmegenHB NijmegenThe Netherlands

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