Abstract
Removal of certain components from pig or cow blood greatly reduces the maturation rate ofTrypanosoma congolense infections inGlossina morsitans fed on such diets. In particular, delipidation of serum has the same effect as complete removal of dietary serum with few midgut infections reaching maturity. The addition of gamma-globulin to red cells partially restores the ability of immature infections to transform suggesting that serum lipids or other serum factors are not acting directly on midgut trypanosome metabolism but indirectly through interactions between dietary constituents and the flies' metabolic processes. As susceptibility toT. congolense infection is known to be maternally inherited inG. morsitans, it is suggested that serum factors act through the flies' symbionts to induce maturation in midgut infections.
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References
Cham BE, Knowles BR (1976) A solvent system for deplidation of plasma or serum without protein precipitation. J Lipid Res 17:176–181
Clarke JE (1969) Trypanosome infection rates in the mouthparts of Zambian tsetse flies. Ann trop Med Parasitol 63:15–34
Downer RGH (1978) Functional role of lipids in insects. In: Rockstein M (ed), Biochemistry of Insects, Academic Press, New York, pp 58–92
Gingrich JB, Ward RA, Macken LM, Schoenbeckler MJ (1982)Trypanosoma brucei rhodesiense (Trhpanosomatidae): factors influencing infection rates of a recent human isolate in the tsetseGlossina morsitans (Diptera: Glossinidae). J Med Entomol 19:268–274
Gooding RH (1974) Digestive processes of haematophagous insects. V. Inhibitors of trypsin fromGlossina morsitans morsitans (Diptera: Glossinidae). Can Ent 106:39–44
Gooding RH (1975) Digestive enzymes and their control in haematophagous arthropods. Acta Trop (Berl) 32:96–111
Gooding RH (1977) Digestive processes of haematophagous insects. XIII. Evidence for the digestive function of midgut proteinases ofGlossina morsitans morsitans Westwood (Diptera: Glossinidae) Can J Zool 55:1557–1562
Harley JMB (1966) Studies on age and Trypanosome infection rates in females ofGlossina pallidipes Aust.,G. palpalis fuscipes Newst. andG. brevipalpis Newst. in Uganda. Bull ent Res 57:23–37
Herbert WJ, Lumsden WHR (1976)Trypanosoma brucei: a rapid “matching method” for estimating the host's parasitaemia. Exp Parasitol 40:427–431
Hoare CA (1970) Systematic description of the mammalian trypanosomes of Africa. In: Mulligan HW (ed), The African Trypanosomiases, George Allen and Unwin, London, pp 24–59
Houseman JG (1980) Anterior midgut proteinase inhibitor fromGlossina morsitans morsitans Westwood (Diptera: Glossinidae) and its effects upon tsetse digestive enzymes. Can J Zool 58:79–87
Jordan AM (1965) The hosts ofGlossina as the main factor affecting Trypanosome infection rates of tsetse flies in Nigeria. Trans R Soc Trop Med Hyg 59:423–431
Jordan AM (1974) Recent developments in the ecology and methods of control of tsetse flies (Glossina spp.) (Dipt., Glossinidae)—a review. Bull ent Res 63:361–399
Jordan AM (1976) Tsetse flies as vectors of trypanosomes. Vet Parasitol 2:143–152
Langley PA (1966) The control of digestion in the tsetse fly,Glossina morsitans. Enzyme activity in relation to the size and nature of the meal. J Insect Physiol 12:439–448
Maudlin I (1982) Inheritance of susceptibility toTrypanosoma congolense infection inGlossina morsitans. Ann trop Med Parasitol 76:225–227
Mews AR, Langley PA, Pimley RW, Flood MET (1977) Large-scale rearing of tsetse flies (Glossina spp.) in the absence of a living host. Bull ent Res 67:119–128
Moloo SK (1981) Effects of maintainingGlossina morsitans morsitans on different hosts upon the vector's subsequent infection rates with pathogenic trypanosomes. Acta Trop 38:125–136
Nelson GJ (1967) Lipid composition of erythrocytes in various mammalian species. Biochim Biophys Acta 144:221–232
Newton BA, Cross GAM, Baker JR (1973) Differentiation in Trypanosomatidae. In: 23rd Symposium of Society for General Microbiology. Cambridge University Press, pp 339–373
Nogge G (1976) Sterility in tsetse flies (Glossina morsitans Westwood) caused by loss of symbionts. Experienta 32:995
Pell PE, Southern DI (1975) Symbionts in the female tsetse flyGlossina morsitans morsitans. Experientia 31:650–651
Wessels JMC, Veerkamp JH (1973) Some aspects of the osmotic lysis of erythrocytes. III. Comparison of glycerol permeability and lipid composition of red blood cell membranes from eight mammalian species. Biochim Biophys Acta 291:190–196
Wigglesworth VB (1929) Digestion in the tsetse fly: A study of structure and function. Parasitology 21:288–321
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Maudlin, I., Kabayo, J.P., Flood, M.E.T. et al. Serum factors and the maturation ofTrypanosoma congolense infections inGlossina morsitans . Z. Parasitenkd. 70, 11–19 (1984). https://doi.org/10.1007/BF00929570
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DOI: https://doi.org/10.1007/BF00929570