Molecular and Cellular Biochemistry

, Volume 124, Issue 2, pp 115–120 | Cite as

Hormonal regulation of sialic acid-binding (SAS) protein synthesis of rat uterus

  • Indrani Chakraborty
  • Purnima Chatterjee
  • Mridula Chowdhury


Sialic acid binding proteins (SAS) of rat uteri have been found in all three stages of the estrous cycle. To study the control of synthesis of these proteins two different animal models were used I-immature female rats (25 d) where the hormones estradiol (E2) and progesterone (P4) were given separately and together, and II-adult female rats where hormone treatment commenced 14 days after ovariectomy. The data indicated that E2 initiated the synthesis of SAS proteins in the immature animals, while P4 could inhibit SAS synthesis, either given alone or together with E2. However, prior priming of the rat with E2 and subsequent administration of P4 stimulated SAS protein synthesis.

Key words

sialic acid binding protein uterus progesterone estradiol 


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Copyright information

© Kluwer Academic Publishers 1993

Authors and Affiliations

  • Indrani Chakraborty
    • 1
  • Purnima Chatterjee
    • 1
  • Mridula Chowdhury
    • 1
  1. 1.Indian Instistute of Chemical BiologyCalcuttaIndia

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