Zeitschrift für Parasitenkunde

, Volume 60, Issue 3, pp 249–261 | Cite as

Pathology ofAnopheles stephensi after infection withPlasmodium berghei berghei

I. Mortality rate
  • Adel M. Gad
  • Walter A. Maier
  • Gerhard Piekarski
Original Investigations


The mortality ofP. berghei-infectedAnopheles stephensi females can be about 30% higher during the first three days than in normal blood-fed mosquitoes. As expected the mortality is higher after feeding on highly infected mice but also depends on the date of feeding and the temperature. Infected mosquitoes kept at 25° C die more often than those kept at 21° C. On the other hand sporozoite production needs the low temperature of 21°C. So the sporozoite production rate falls with increasing temperature, and the mortality rate increases.


Mortality Rate Production Rate Rate Increase Infected Mouse Mortality Rate Increase 
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Zur Pathologie vonAnopheles stephensi nach Infektion mitPlasmodium berghei berghei

I. Mortalität


Ein Vergleich der Mortalitätsrate derAnopheles-Mücken während der Plasmodien-Entwicklung zeigt, daß die Sterblichkeit in den ersten drei Tagen um ca. 30% höher sein kann als bei Kontrolltieren, die mit normalem Blut gefüttert worden waren. Sie ist erwartungsgemäß um so höher, je größer die Parasitämie im Blut der Spendermaus war. Allerdings spielt neben dem Fütterungszeitpunkt die Temperatur eine wichtige Rolle. Infizierte Mücken sterben bei 25°C weit häufiger als bei 21°C; Sporozoitenbildung findet aber bei 21°C statt. Die Fähigkeit zur Sporozoitenbildung nimmt also mit steigender Temperatur ab, die Mortalität zu.


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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Adel M. Gad
    • 1
  • Walter A. Maier
    • 1
  • Gerhard Piekarski
    • 1
  1. 1.Institut für Medizinische Parasitologie der UniversitätBonn 1Federal Republic of Germany

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