Advertisement

Parasitology Research

, Volume 77, Issue 8, pp 720–722 | Cite as

The native form of thePlasmodium falciparum Pf68 neutral proteinase is a 105,000-Da polypeptide

  • Philippe Lawton
  • Christine Barrault
  • Philippe Grellier
  • Joseph Schrével
  • Hans-G. Heidrich
Short Communications

Keywords

Polypeptide Native Form Neutral Proteinase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Braun-Breton C, Rosenberry TL, Pereira da Silva L (1988) Induction of the proteolytic activity of a membrane protein inPlasmodium falciparum by phosphatidyl inositol-specific phospholipase C. Nature 332:457–459Google Scholar
  2. Cooper JA, Ingram LT, Bushell GR, Fardoulys CA, Stenzel D, Schofield L, Saul AJ (1988) The 140/130/105-kilodalton protein complex in the rhoptries ofPlasmodium falciparum consists of discrete polypeptides. Mol Biochem Parasitol 29:251–260Google Scholar
  3. Cooper JA, Atkins A, Saul AJ (1989) N-terminal amino acid sequencing of the 105-kilodalton rhoptry antigen ofPlasmodium falciparum. Mol Biochem Parasitol 33:203–204Google Scholar
  4. Deguercy A, Hommel M, Schrével J (1990) Purification and characterization of 37 kilodalton proteases fromPlasmodium falciparum andPlasmodium berghei which cleave erythrocyte cytoskeletal components. Mol Biochem Parasitol 38:233–244Google Scholar
  5. Grellier P, Picard I, Bernard F, Mayer R, Heidrich HG, Monsigny M, Schrével J (1989) Purification and identification of a neutral endopeptidase inPlasmodium falciparum schizonts and merozoites. Parasitol Res 75:455–460Google Scholar
  6. Heidrich HG, Strych W, Mrema JEK (1983) Identification of surface and internal antigens from spontaneously releasedPlasmodium falciparum merozoites by radio-iodination and metabolic labeling. Z. Parasitenkd 69:715–725Google Scholar
  7. Rosenthal PJ, McKerrow JM, Aikawa M, Nagasawa H, Leech JH (1988) A malarial cysteine proteinase is necessary for hemoglobin degradation byPlasmodium falciparum. J Clin Invest 82:1560–1566Google Scholar
  8. Rothe GM (1988) Determination of molecular masses, Stockes's radius, frictional coefficient and isomer type of non-denatured proteins by time-dependent pore gradient gel electrophoresis. Electrophoresis 9:307–316Google Scholar
  9. Schrével J, Deguercy A, Mayer R, Monsigny M (1990) Proteases in malaria-infected red blood cells. Blood Cells 16:563–584Google Scholar
  10. Vander Jagt DL, Hunsaker LA, Campos NM (1986) Characterization of a hemoglobin-degrading, low molecular weight protease fromPlasmodium falciparum. Mol Biochem Parasitol 18:389–400Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Philippe Lawton
    • 1
  • Christine Barrault
    • 2
  • Philippe Grellier
    • 2
  • Joseph Schrével
    • 2
    • 3
  • Hans-G. Heidrich
    • 1
  1. 1.Max-Planck-Institut für BiochemieMartinsriedFederal Republic of Germany
  2. 2.Laboratoire de Biologie CellulaireUniversité de PoitiersPoitiersFrance
  3. 3.Museum National d'Histoire NaturelleParisFrance

Personalised recommendations