Synchronous-process diagrams for nucleophilic addition to carbonyl compounds

  • K. Ya. Burshtein
  • Yu. I. Khurgin
Physical Chemistry


  1. 1.

    A graphic method for representing system movement along the reaction coordinate has been developed for studying the synchronous processes of protonation and deprotonation in nucleophilic reactions of carbonyl compounds.

  2. 2.

    In the case of uncharged-particle reactions, alteration of the pH of the medium will alter the distance of reactant separation required for protonation and deprotonation, and thereby change the reaction rate.



Carbonyl Carbonyl Compound Graphic Method Reaction Coordinate System Movement 
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Literature cited

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Copyright information

© Plenum Publishing CorporationPlenum Publishing Corporation 1978

Authors and Affiliations

  • K. Ya. Burshtein
    • 1
  • Yu. I. Khurgin
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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