Molecular and Cellular Biochemistry

, Volume 140, Issue 1, pp 73–79

Antioxidant properties of dehydrozingerone and curcumin in rat brain homogenates

  • D. V. Rajakumar
  • M. N. A. Rao

DOI: 10.1007/BF00928368

Cite this article as:
Rajakumar, D.V. & Rao, M.N.A. Mol Cell Biochem (1994) 140: 73. doi:10.1007/BF00928368


The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneous lipid peroxidation. These compounds also inhibited lipid peroxidation induced by ferrous ions, ferric-ascorbate and ferric-ADP-ascorbate. In all these cases, curcumin was more active than dehydrozingerone and dl-α-tocopherol.

Key words

curcumin dehydrozingerone lipid peroxidation conjugated dienes antioxidants 

Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • D. V. Rajakumar
    • 1
  • M. N. A. Rao
    • 1
  1. 1.Department of Pharmaceutical ChemistryCollege of Pharmaceutical SciencesManipalIndia

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