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Application of antigens fromTaenia hydatigena cyst fluid for the immunodiagnosis of human hydatidosis

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Abstract

Fluid was collected from cysts ofTaenia hydatigena in 60 adult sheep and fluid from each animal pooled separately. By double diffusion antigen 5 was demonstrated in all pools but one. The criteria are described for selection and standardization of these preparations for use as antigens for the immunodiagnosis of human hydatid disease. Sera from 50 persons harbouring hydatid cysts and from 50 patients with other disease conditions were examined by the arc-5 double-diffusion test, using two antigens prepared fromEchinococcus granulosus andT. hydatigena cyst fluids, respectively. The results showed that a higher diagnostic sensitivity was obtained with the hydatid antigen. The significance of the findings is discussed in terms of their application to human immunodiagnosis in areas where hydatidosis, but not cysticercosis, is rare in livestock.

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Authors and Affiliations

  1. Gobierno de Formosa, Conicet, Fundanord, Centro de Diagnóstico e Investigaciones Veterinarias Formosa (CEDIVEF), Casilla 292, 3600, Formosa, Argentina

    C. M. Monzón

  2. Pan American Zoonoses Center, Pan American Health Organization/World Health Organization, Casilla 3092, Correo Central, 1000, Buenos Aires, Argentina

    E. A. Coltorti & V. M. Varela-Díaz

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  1. C. M. Monzón
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  2. E. A. Coltorti
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  3. V. M. Varela-Díaz
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Monzón, C.M., Coltorti, E.A. & Varela-Díaz, V.M. Application of antigens fromTaenia hydatigena cyst fluid for the immunodiagnosis of human hydatidosis. Z. Parasitenkd. 71, 533–537 (1985). https://doi.org/10.1007/BF00928356

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