Zeitschrift für Parasitenkunde

, Volume 71, Issue 4, pp 429–433 | Cite as

Effect of poly-l-lysine and neuraminidase on the infectivity ofTrypanosoma cruzi in cultured HeLa cells

  • F. Gamarro
  • S. Castanys
  • L. M. Ruiz-Perez
  • F. J. Adroher
  • A. Osuna
Original Investigations


The percentage of parasitisation and index of adherence ofTrypanosoma cruzi has been studied when host HeLa cells or metacyclic forms were pretreated with neuraminidase or with poly-l-lysine. The percentage of parasitisation was significatively reduced (P≦0.001) when cells were pretreated with poly-l-lysine while pretreatment with neuraminidase caused no apparent effects. On the other hand, the adherence of the metacyclic forms pretreated with poly-l-lysine or neuraminidase was significantly higher than that of the control group.


HeLa Cell Apparent Effect Culture HeLa Cell Metacyclic Form 
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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • F. Gamarro
    • 1
  • S. Castanys
    • 1
  • L. M. Ruiz-Perez
    • 1
  • F. J. Adroher
    • 1
  • A. Osuna
    • 1
  1. 1.Department of Parasitology, Faculty of PharmacyUniversity of GranadaGranadaSpain

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