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Zeitschrift für Parasitenkunde

, Volume 71, Issue 4, pp 429–433 | Cite as

Effect of poly-l-lysine and neuraminidase on the infectivity ofTrypanosoma cruzi in cultured HeLa cells

  • F. Gamarro
  • S. Castanys
  • L. M. Ruiz-Perez
  • F. J. Adroher
  • A. Osuna
Original Investigations

Abstract

The percentage of parasitisation and index of adherence ofTrypanosoma cruzi has been studied when host HeLa cells or metacyclic forms were pretreated with neuraminidase or with poly-l-lysine. The percentage of parasitisation was significatively reduced (P≦0.001) when cells were pretreated with poly-l-lysine while pretreatment with neuraminidase caused no apparent effects. On the other hand, the adherence of the metacyclic forms pretreated with poly-l-lysine or neuraminidase was significantly higher than that of the control group.

Keywords

HeLa Cell Apparent Effect Culture HeLa Cell Metacyclic Form 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • F. Gamarro
    • 1
  • S. Castanys
    • 1
  • L. M. Ruiz-Perez
    • 1
  • F. J. Adroher
    • 1
  • A. Osuna
    • 1
  1. 1.Department of Parasitology, Faculty of PharmacyUniversity of GranadaGranadaSpain

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