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Double diffusion analysis of antigens released fromPlasmodium knowlesi in vitro

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Abstract

Two parasite-derived antigens (designated band 1 and band 2) were identified upon double-diffusion analysis of culture medium from reinvading cultures ofP. knowlesi. Band 1 antigen showed characteristics with the R-antigens ofP. falciparum while the other was similar to theP. falciparum L-antigens. Both antigens appeared to be largely particulate in character and did not display any obvious variant-specificity. Analysis of plasma from rhesus monkeys infected with the same antigenic variant showed the presence of band 1 antigen only.

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Author notes

  1. A. A. McColm

    Present address: Department of Parasitology, The Wellcome Research Laboratories, Beckenham, Kent, UK

  2. P. I. Trigg

    Present address: World Health Organization, Geneva, Switzerland

Authors and Affiliations

  1. Division of Parasitology, National Institute for Medical Research, Mill Hill, NW7 1AA, London, UK

    A. A. McColm & P. I. Trigg

Authors
  1. A. A. McColm
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  2. P. I. Trigg
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McColm, A.A., Trigg, P.I. Double diffusion analysis of antigens released fromPlasmodium knowlesi in vitro. Z. Parasitenkd. 64, 353–357 (1981). https://doi.org/10.1007/BF00927382

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  • DOI: https://doi.org/10.1007/BF00927382

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