Abstract
The presence of 5-Hydroxymethyluracil which replaces important fractions of thymine in Dinoflagellate DNA is analyzed according to different procaryotic models of biosynthesis. The detection of HOMeU inAmphidinum carterae cells suggests an incorporation of this 5th base during polymerisation of DNA chains rather than a post-synthetic modification of thymines. A relationship between HOMeU and the permanent repair-like DNA synthesis observed inA. carterae is discussed.
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Galleron, C. The fifth base: A natural feature of dinoflagellate DNA. Origins Life Evol Biosphere 13, 195–203 (1984). https://doi.org/10.1007/BF00927171
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DOI: https://doi.org/10.1007/BF00927171