Zeitschrift für Parasitenkunde

, Volume 64, Issue 1, pp 85–93 | Cite as

Humoral suppression inTrypanosoma cruzi infection in relation to the timing of antigen presentation

  • A. C. Corsini
  • Odete L. P. Oliveira
  • M. G. Costa
Original Investigations

Abstract

(CBA×C57 B1/10)F1 mice infected intraperitoneally with 100 parasites ofTrypanosoma cruzi strain Y developed an infection with acute and chronic phases. Humoral suppression to sheep red blood cells was evident in both phases but enhancement of the response was achieved only at the beginning of the infection. A mitogen secreted by the parasite could explain both phenomenons.

Key words

Trypanosoma cruzi Immunosuppression Immunenhancement Mice 

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Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • A. C. Corsini
    • 1
  • Odete L. P. Oliveira
    • 1
  • M. G. Costa
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of Campinas-UNICAMPCampinasBrazil

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