Abstract
The evolution of the genetic code is an extremely complex problem. The addition of a new method by which the code could evolve, however, allows much to be explained about the way in which the present codes (Γ3 and Γ ⋆3 ) originated. The idea that ambiguity would allow the length of the codon to change is very useful, since it predicts the distribution of the 4-blocs and 2-blocs in the code, determines where variations in the code are probable, and presents a scenario for the evolution of the code.
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Kocherlakota, R.R., Acland, N.D. Ambiguity and the evolution of the genetic code. Origins Life Evol Biosphere 12, 71–80 (1982). https://doi.org/10.1007/BF00926913
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DOI: https://doi.org/10.1007/BF00926913