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Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides

Communication 14. Aminoacylation of oligonucleotides that enter into the composition of the acceptor end of tRNA

  • Organic and Biological Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    Cytidylyl-(3'-5')-cytidylyl-(3'-5')-adenosine 5'-phosphite (piCpCpA) was synthesized, which was characterized by the UV spectrum and the enzymatic hydrolysis data.

  2. 2.

    The 3'(2')-alanine ester is formed predominantly when cytidylyl-(3'-5')-adenosine is aminoacylated with alanine trifluoroacetate imidazolide. The terminal adenosine derivative' is not formed when piCpCpA is aminoacylated.

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Literature cited

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Authors and Affiliations

  1. Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow

    N. B. Tarusova, T. L. Tsilevich & B. P. Gottikh

Authors
  1. N. B. Tarusova
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  2. T. L. Tsilevich
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  3. B. P. Gottikh
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Additional information

See [1] for Communication 13.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 135–138, January, 1975.

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Tarusova, N.B., Tsilevich, T.L. & Gottikh, B.P. Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides. Russ Chem Bull 24, 124–127 (1975). https://doi.org/10.1007/BF00926306

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  • DOI: https://doi.org/10.1007/BF00926306

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