Conclusions
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1.
The aminomethylation and azo-coupling of 5-benzyl-3-hydroxypyridine take place at the 2 position of theβ-pyridinol ring.
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2.
The presence of a benzyl group in the 5 position of theβ-pyridinol ring prevents both aminomethylation and azo-coupling in the 6 position.
Literature cited
L. D. Smirnov, V. S. Zhuravlev, E. E. Merzon, B. E. Zaitsev, and K. M. Dyumaev, Khim. Geterotsikl. Soedin., 518 (1973).
L. D. Smirnov, V. P. Lezina, and K. M. Dyumaev, Izv. Akad. Nauk SSSR, Ser. Khim., 198 (1965).
J. A. Moore and F. I. Marascia, J. Am. Chem. Soc.,81, 6049 (1959).
R. A. Abramovich and J. Saha, Advan. Heterocycl. Chem.,6, 229 (1966).
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Translated from Izvestiya Akademii Nauk $SSR, Seriya Khimicheskaya, No. 12, pp. 2801–2803, December, 1973.
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Smirnov, L.D., Zhuravlev, V.S., Lezina, V.P. et al. Aminomethylation and azo-coupling reactions of 5-benzyl-3-hydroxypyridine. Russ Chem Bull 22, 2737–2738 (1973). https://doi.org/10.1007/BF00926154
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DOI: https://doi.org/10.1007/BF00926154