Conclusions
The acylation of benzene with 5-bromonicotinoyl chloride gave 5-bromo-3-benzoylpyridine in high yield, the Kizhner reduction of which led to the synthesis of 3-hydroxy-5-benzylpyridine in good yield.
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Literature cited
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No.1, pp.222–224, January, 1976.
The authors thank N. M. Émanuél' for his constant interest in the work.
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Zhuravlev, V.S., Smirnov, L.D., Lezina, V.P. et al. Synthesis of 5-benzyl-3-hydroxypyridine and its N-oxide. Russ Chem Bull 25, 217–219 (1976). https://doi.org/10.1007/BF00925662
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DOI: https://doi.org/10.1007/BF00925662