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Kinetics of heat inactivation of trypsin in complex with poly-4(5)-vinylimidazole

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A study was made of the irreversible heat inactivation of free trypsin, and of trypsin in the complex with poly-4(5)-vinylimidazole, in aqueous solution, at pH 6.1, in the temperature range 33–50°.

  2. 2.

    The inactivation rate of trypsin decreases in the presence of the polymer, and its activation enthalpy increases when compared with the values of these parameters for free trypsin.

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Literature cited

  1. S. V. Kol'tsova, N. G. Illarionova, E. F. Panarin, G. D. Rudkovskaya, and G. V. Samsonov, Izv. Akad. Nauk SSSR, Ser. Khim., 643 (1975).

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Authors and Affiliations

  1. Institute of High-Molecular-Weight Compounds, Academy of Sciences of the USSR, Leningrad

    S. V. Kol'tsova & G. V. Samsonov

Authors
  1. S. V. Kol'tsova
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  2. G. V. Samsonov
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No.1, pp.168–171, January, 1976.

We express our gratitude to G. D. Rudkovskaya for graciously supplying the sample of P4VI.

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Kol'tsova, S.V., Samsonov, G.V. Kinetics of heat inactivation of trypsin in complex with poly-4(5)-vinylimidazole. Russ Chem Bull 25, 157–159 (1976). https://doi.org/10.1007/BF00925641

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  • DOI: https://doi.org/10.1007/BF00925641

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