Asymmetric hydrogenation of acetoacetic ester on raney cobalt and copper catalysts modified with D-(+)-tartaric acid

  • V. I. Neupokoev
  • Yu. I. Petrov
  • E. I. Klabunovskii
Organic and Biological Chemistry
  • 28 Downloads

Conclusions

  1. 1.

    On Raney Cu and Co catalysts modified with D-(+)-tartaric acid acetoacetic ester is hydrogenated asymmetrically.

     
  2. 2.

    The optical yield of (-)-ethyl-3-hydroxybutyrate depends on the nature of the catalyst and the experimental conditions: on Cu catalyst the optical yield reaches 20–24% and is close to the optical yield obtained on modified Ni catalyst: on Co catalyst the optical yield is considerably less (2–8%). With increase in the quantity of catalyst the optical yield on these catalysts passes through a maximum.

     

Keywords

Hydrogenation Copper Ester Cobalt Tartaric Acid 

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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • V. I. Neupokoev
    • 1
  • Yu. I. Petrov
    • 1
  • E. I. Klabunovskii
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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