Conclusions
A method, based on the addition of Grignard reagent to cyclopropene hydrocarbons, was proposed for the synthesis of alkyl-, phenyl-, and alkenylcyclopropanecarboxylic acids that bear a geminal dimethyl grouping in the ring.
Literature cited
M. Elliott, Bull. World Health Organ.,44, 315 (1971).
M. Yu. Lukina, T. Yu. Rudashevskaya, and O. A. Nesmeyanova, Dokl. Akad. Nauk SSSR,190, 1109 (1970).
P. Binger, Synthesis,1974, 190.
G. L. Closs, L. E. Closs, and W. A. Böll, J. Am. Chem. Soc,85, 3796 (1963).
J. Meisenheimer, Ber.,61, 708 (1928).
P. S. Warton and T. J. Bair, J. Org. Chem.,30, 1681 (1965).
J. Roberts, J. Am. Chem. Soc,85, 3218 (1963).
A. Bramwell, L. Crombie, P. Hemesley, G. Pattenden, M. Elliott, and N. Janes, Tetrahedron,25, 1727 (1969).
A. P. Meshcheryakov and I. E. Dolgii, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk,1960, 931.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 669–671, March, 1979.
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Rudashevskaya, T.Y., Nesmeyanova, O.A. Preparation of substituted gem-dimethylcyclopropanecarboxylic acids. Russ Chem Bull 28, 624–625 (1979). https://doi.org/10.1007/BF00924855
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DOI: https://doi.org/10.1007/BF00924855