Conclusions
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1.
The method of activated ethers was used to synthesize a polypeptide containing the -Glu-Tyrsequence, and with an average molecular weight (Mav) of ∼4000.
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2.
Increasing the amount of triethylamine in the polycondensation reaction failed to lead to an increase in Mav.
Literature cited
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J. Kovacs, G. N. Schmit, and U. R. Chatak, Biopolymers,6, 817 (1968).
L. Zervas, D. Borovas, and E. Garis, J. Am. Chem. Soc.,85, 3660 (1963).
C. W. Pifer and E. G. Wollis, Anal. Chem.,24, 300 (1952).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 442–444, February, 1974.
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Shibnev, V.A., Ismailov, M.I. & Zegel'man, A.B. Synthesis of regular polypeptide H-(Glu-Tyr)n-OH by the method of activated ethers. Russ Chem Bull 23, 411–412 (1974). https://doi.org/10.1007/BF00924701
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DOI: https://doi.org/10.1007/BF00924701