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Synthesis and reaction of some S-alkyl diphenylthiophosphinates with acetylcholinesterase

  • Organic and Biological Chemistry
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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A number of S-alkyl diphenylthiophosphinates was synthesized and their inhibiting activity toward acetytcholinesterase was studied.

  2. 2.

    The obtained compounds are capable of both reversible and irreversible inhibition of the catalytic activity of acetylcholinesterase.

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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 407–411, February, 1974.

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Agabekyan, R.S., Berkhamov, M.K., Godovikov, N.N. et al. Synthesis and reaction of some S-alkyl diphenylthiophosphinates with acetylcholinesterase. Russ Chem Bull 23, 374–377 (1974). https://doi.org/10.1007/BF00924691

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  • DOI: https://doi.org/10.1007/BF00924691

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