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Fluorination of alkylamidine hydrochlorides with elemental fluorine

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

Conditions were found for selectively fluorinating the guanyl group of alkyl-substituted amidines with elemental fluorine without touching the alkyl radical.

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Literature cited

  1. A. V. Fokin, Yu. N. St'udnev, and L. L. Kuznetsova, Reactions and Methods for Studying Organic Compounds [in Russian], Vol. 24, Khimiya (1976), p. 39.

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  2. D. L. Ross, C. L. Coon, and M. E. Hill, J. Org. Chem.,35, 3093 (1970).

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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2139–2141, September, 1977.

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Fokin, A.V., Stolyarov, V.P., Komarov, V.A. et al. Fluorination of alkylamidine hydrochlorides with elemental fluorine. Russ Chem Bull 26, 1981–1983 (1977). https://doi.org/10.1007/BF00924410

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  • DOI: https://doi.org/10.1007/BF00924410

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