Conclusions
A path was found for the synthesis of 17α-chloro-16α-amino-20-ketosteroids and their acetates by the stereospecific cis-opening of 16,17α-epimino-20-ketosteroids with hydrochloric acid.
Literature cited
Hoff Dall, R., J. Org. Chem.35, 2263 (1970).
A. V. Kamernitskii, A. M. Turuta, and T. M. Fadeeva, Izv. Akad. Nauk SSSR, Ser. Khim., 1132 (1976).
D. Kal'sines, A. V. Kamernitskii, and A. M. Turuta, Izv. Akad. Nauk SSSR, Ser. Khim., 1838 (1976).
D. Kal'sines, A. V. Kamernitskii, and A. M. Turuta, Izv. Akad. Nauk SSSR, Ser. Khim., 1841 (1976).
A. V. Kamernitskii, D. Kal'sines, and A. M. Turuta, Izv. Akad. Nauk SSSR, Ser. Khim., 2090 (1977).
V. R. Mattox and R. C. Kendall, J. Am. Chem. Soc.,72, 2290 (1950).
F. Ramires and A. F. Kirby, J. Am. Chem. Soc.,75, 6026 (1953).
C. Djerassi, Optical Rotatory Dispersion [Russian translation], IL (1962), p. 166.
Author information
Authors and Affiliations
Additional information
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2128–2130, September, 1977.
Rights and permissions
About this article
Cite this article
Kamernitskii, A.V., Kal'sines, D., Turuta, A.M. et al. Synthesis of 17α-chloro-16-α-amino-20-ketosteroids. Russ Chem Bull 26, 1971–1973 (1977). https://doi.org/10.1007/BF00924406
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00924406