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Synthesis of O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides and their interactions with choline esterases

  • Organic Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A number of O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides have been synthesized.

  2. 2.

    The O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides were found to be reversible inhibitors of acetylcholinesterase and butyrylcholinesterase of a competitive type.

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Literature cited

  1. R. S. Agabekyan, M. Kh. Bekanov, M. Kh. Berkhamov, N. N. Godovikov, and M. I. Kabachnik, Izv. Akad. Nauk SSSR, Ser. Khim., 874 (1974).

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Authors and Affiliations

  1. Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, Moscow

    M. Kh. Berkhamov, V. M. Kuzamyshev, N. N. Godovikov, R. S. Agabekyan, E. G. Kireeva, V. G. Zhasminova, Kh. Kh. Gurdaliev & M. I. Kabachnik

Authors
  1. M. Kh. Berkhamov
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  2. V. M. Kuzamyshev
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  3. N. N. Godovikov
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  4. R. S. Agabekyan
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  5. E. G. Kireeva
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  6. V. G. Zhasminova
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  7. Kh. Kh. Gurdaliev
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  8. M. I. Kabachnik
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2095–2098, September, 1977.

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Berkhamov, M.K., Kuzamyshev, V.M., Godovikov, N.N. et al. Synthesis of O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides and their interactions with choline esterases. Russ Chem Bull 26, 1939–1942 (1977). https://doi.org/10.1007/BF00924394

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  • DOI: https://doi.org/10.1007/BF00924394

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