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Modified steroids 103. Splitting of the 17-C-N bond of 16,17α-epimino-20-ketgsteroids and their 20-hydrazones by reaction with thioacetic acid

  • A. V. Kamernitskii
  • A. M. Turupa
  • T. M. Fadeeva
  • V. A. Pavlov
Organic Chemistry
  • 22 Downloads

Conclusions

  1. 1.

    The reactions of 16,17α-eplminopregn-5-en-3β-ol-20-one and its 20-carbethoxyhydrazone with thioacetic acid proceed with different stereochemical direction of scission of the aziridine ring at the tertiary 17-C atom. Schemes to explain the differences are proposed.

     
  2. 2.

    A new class of heterocyclic compounds, 2′-methyl-[16,17α-d]-thiazoline 20-ketosteroids, has been obtained.

     

Keywords

Methyl Steroid Scission Heterocyclic Compound Aziridine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • A. V. Kamernitskii
    • 1
  • A. M. Turupa
    • 1
  • T. M. Fadeeva
    • 1
  • V. A. Pavlov
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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