Conclusions
Some 2-oxo-2-pyrrolidino-1,3,2-dioxaphospholanes and the corresponding phosphorinanes, and also some 2-thio-2-pyrrolidino-1,3,2-dioxaphospholanes (phosphorinanes), were obtained for the first time. These compounds have an antispasmodic effect and the ability to depress the central nervous system.
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Literature cited
N. P. Grechkin and L. N. Grishina, Izv. Akad. Nauk SSSR, Ser. Khim., 1670 (1973).
F. R. Atherton, H. P. Openshaw, and A. R. Todd, J. Chem. Soc., 660 (1945).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, pp. 1898–1900, August, 1974.
The authors express their gratitude to I. D. Neklesova, M. A. Kudrina, and N. V. Egorova, coworkers in the toxicological laboratory, for studying the physiological activity of the compounds.
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Grechkin, N.P., Grishina, L.N. Organophosphorus derivatives of pyrrolidine. Russ Chem Bull 23, 1824–1825 (1974). https://doi.org/10.1007/BF00923225
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DOI: https://doi.org/10.1007/BF00923225