Conclusions
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1.
The new model compounds: 3-(3′-O-acetylthymidine-5′-phospho)-1,3-butanediol-1-(p-nitrophenyl) phosphate, 1-(thymidine-5′-phospho)-1,4-butanediol-4-phosphate and bis-(phenylphospho)-1,4-butanediol were synthesized for studying the mechanism of the action of exonuclease A5.
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2.
The structure of the synthesized compounds was proved by the enzymolytic method, and also employing UV and NMR spectroscopy.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1375–1379, June, 1974.
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Mikhailov, S.N., Kozlov, I.A., Ledneva, R.K. et al. Synthesis of model compounds for studying the mechanism of the action of exonuclease A5. Russ Chem Bull 23, 1294–1298 (1974). https://doi.org/10.1007/BF00923100
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DOI: https://doi.org/10.1007/BF00923100