Catalytic synthesis of optically active phenylglycine by hydrogenation of C=N bond in R-Menthyl phenylglyoxylate oxime
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A study was made of the asymmetric hydrogenation of the oxime of R-menthyl phenylglyoxylate on Pd(OH)2/C catalyst at atmospheric pressure and 25° in ethanol.
The stereodirectivity of the process changes during reaction; the possible stereochemical mechanism of the addition of hydrogen is discussed.
KeywordsHydrogenation Oxime Process Change Catalytic Synthesis Asymmetric Hydrogenation
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