Conclusions
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1.
Five peptide fragments which include the Ser38 residue of the histone H1 fraction have been synthesized. These are; H-Lysn-Ala-Ser-R, H-Lys3-Gly-Ser-R, H-Lys3-Ala-Ala-Ser-R, and R-Gly-Pro-Pro-OCH3, where n=1 to 3, and H-Lysn-Ala-Ser-OCH3, where n=1 or 3.
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2.
Preliminary experiments have shown the only H-Lys3-Ala-Ala-Ser-R and H-Lysn-Ala-Ser-OCH3, where n=1 or 3, were not phosphorylated by phosphokinase.
Literature cited
T. A. Langan, Proc. Nat. Acad. Sci. USA,64, 1276 (1969).
L. I. Mar'yash and V. A. Shibnev, Izv, Akad. Nauk SSSR, Ser. Khim., 1858 (1972).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Biologicheskaya, No. 4, pp. 916–917, April, 1976.
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Shibnev, V.A., Turaev, O.D. Synthesis of se rine-containing fragments of the histone H1 fraction. Russ Chem Bull 25, 894–895 (1976). https://doi.org/10.1007/BF00922407
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DOI: https://doi.org/10.1007/BF00922407