Conclusions
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1.
The corresponding 1,3-bis[ω-(p-toluenesulfonamido)alkyl]uracils are formed as a result of the reaction of 1, 3-bis(ω-bromoalkyl)uracils and the Na salt of p-toluenesulfamide.
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2.
Interaction of l-(ω-bromobutyl)uracil with p-toluenesulfamide in a medium of n-butanol leads to formation of 9,18,19,20-tetraoxo-1,6,10,15-tetraazatricyclo[13.3.1.16.10]-eicosa-7, I6-diene,l-(ω-hydroxybutyl)-2-butoxypyrimid-4-one, and l-(ω-hydroxybutyl)-2-p-toluenesulfonamidopyrimid-4-one.
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Literature cited
J. Wempen, R. Duschinsky, L. Kaplan, and J. J. Fox, J. Amer. Chem. Soc.,83, 4755 (1961).
K. Raid, Course of Physical Organic.Chemistry [in Russian], Mir (1972), p. 415, 445.
G. Kenner and A. Todd, Heterocyclic Compounds [Russian translation], R. Elderfield (ediizor), Izd. IL, (1960), Vol. 6, p. 229.
M. Horak and J. Gut, Collect. Czech. Chem. Communs,26, 1680 (1961).
D. Shugar and J. J. Fox, Biochim. et Biophys. Acta,9, 199 (1952).
J. Pitha, J. Org. Chem.,35, 903 (1970).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1103–1106, May, 1976.
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Shvetsov, Y.S., Shirshov, A.N. & Reznik, V.S. Synthesis and properties of pyrimidinylalkylsulfonamides. Russ Chem Bull 25, 1072–1075 (1976). https://doi.org/10.1007/BF00921995
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DOI: https://doi.org/10.1007/BF00921995