Abstract
An animal model in the rabbit eye was utilized to study mobilization and relocation of the fovea as a potentially beneficial surgical approach to age-related macular disease. After lentectomy and vitrectomy, the retina was completely separated from the pigment epithelium by means of infusion into the subretinal space. A 360° peripheral retinotomy was performed. The retina was rotated up to 60° around the optic nerve as axis and reattached. Scanning and transmission electron microscopy revealed the relative intactness of outer segments and pigment epithelium after this procedure, both acutely and 3 days following reattachment.
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Machemer, R., Steinhorst, U.H. Retinal separation, retinotomy, and macular relocation I. Experimental studies in the rabbit eye. Graefe's Arch Clin Exp Ophthalmol 231, 629–634 (1993). https://doi.org/10.1007/BF00921956
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DOI: https://doi.org/10.1007/BF00921956