Skip to main content
SpringerLink
Log in

Production, growth and handling of multicellular tumor spheroids

  • Published:
TCA manual / Tissue Culture Association

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Sutherland, R. M., and R. E. Durand. 1976. Radiation response of multicell spheroids —anin vitro tumor model. Curr. Top. Radiat. Res. 11: 87–139.

    Google Scholar 

  2. Durand, R. E., and R. M. Sutherland. 1972. Effects of intercellular contact on radiation damage. Exp. Cell Res.71: 75–80.

    Google Scholar 

  3. Folkman, J., and M. Hochberg. 1973. Selfregulation of growth in three dimensions. J. Exp. Med. 138: 745–753.

    Google Scholar 

  4. Sutherland, R. M., J. A. McCredie, and W. R. Inch. 1971. Growth of multicell spheroids in tissue culture as a model for nodular carcinoma. J. Nat. Cancer Inst. 46: 113–120.

    Google Scholar 

  5. Sutherland, R. M., and R. E. Durand. 1973. Hypoxic cells in anin vitro tumor model. Int. J. Radiat. Biol. 23: 235–246.

    Google Scholar 

  6. Yuhas, J. M., A. P. Li, A. O. Martinez, and A. J. Ladman. 1977. A simplified method for the production and growth of multicellular tumor spheroids. Cancer Res. 37: 3639–3643.

    Google Scholar 

  7. Yuhas, J. M., A. E. Tarleton, and K. B. Molzen. 1978. Multicellular tumor spheroid formation by breast cancer cells isolated from different sites. Cancer Res. 38: 2486–2491.

    Google Scholar 

  8. Putman, D. L., D. K. Park, J. S. Rhim, A. F. Steur, and R. C. Ting. 1977. Correlation of cellular aggregation of transformed cells with their growth in soft agar and tumorigenic potential. Proc. Soc. Exp. Biol. Med. 155: 487–494.

    Google Scholar 

  9. Handschack, W., J. Kopp, and C. Pita. 1977. A simple method for cloning and replica plating of mammalian cells using multicellular spheroids. Acta Biol. Med. Ger. 36: 1429–1434.

    Google Scholar 

  10. Woodman, P. W. 1979. Multicellular tumor spheroids (MTS) asin vitro-models for human colorectal carcinomas (abstr.). Proc. Am. Assoc. Cancer Res. 20: 40.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Biochemical and Clinical Pharmacology, St. Jude Children's Research Hospital, 332 North Lauderdale, P.O. Box 318, 38101, Memphis, Tennessee

    Peter W. Woodman & Michael D. Armour

Authors
  1. Peter W. Woodman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Michael D. Armour
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Woodman, P.W., Armour, M.D. Production, growth and handling of multicellular tumor spheroids. Tca Manual 5, 1161–1163 (1979). https://doi.org/10.1007/BF00920578

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00920578

Key words

Search

Navigation