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Does the erythrocyte sedimentation rate correlate with levels of known plasma proteins?

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Abstract

In order to determine if the ESR correlated with concentrations in plasma of fibrinogen, alpha-1, alpha-2, beta, and gamma globulins, a prospective study of 61 hospitalized patients was undertaken. The correlation coefficient between the ESR and fibrinogen (r=0.4320), alpha-1 globulins 0=0.3763), alpha-2 globulins (r=0.5874), beta globulins (r=0.2156) and gamma globulins (r=0.2169) were determined. The multiple coefficient of correlation was 0.750, and the proportion of variance for all substances measures accounted for only 56% of the ESR. The data suggest that serum substances that were not measured in this study had a significant influence on the ESR.

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Authors and Affiliations

  1. Department of Medicine, Division of Rheumatology, New York University Medical Center, New York, New York

    Stephen Honig & Harry Bartfeld

  2. Department of Medicine, Division of Connective Tissue Disease, St. Vincent's Hospital and Medical Center, New York, New York

    Stephen Honig & Harry Bartfeld

Authors
  1. Stephen Honig
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  2. Harry Bartfeld
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Honig, S., Bartfeld, H. Does the erythrocyte sedimentation rate correlate with levels of known plasma proteins?. Inflammation 1, 409–414 (1976). https://doi.org/10.1007/BF00920339

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