The effect of short versus long exposure times of argon laser panretinal photocoagulation on proliferative diabetic retinopathy
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Abstract
We performed a randomized clinical trial comparing short-duration (0.1 s) with long-duration (0.5 s) bluegreen argon laser burns to deliver panretinal photocoagulation (PRP) in eyes suffering from proliferative diabetic retinopathy with high risk characteristics. We studied 19 eyes in the 0.1-s group and 24 eyes in the 0.5-s group for 6 months. Two or more lines of acuity were lost by 20% of the 0.1-s PRP eyes, but by only 8% of the 0.5-s PRP eyes; New or increased vitreous hemorrhages occurred in 30% of the 0.1-s PRP eyes, but in only 16% of the 0.5-s PRP eyes; New or increased traction retinal detachments did not occur in the 0.1-s PRP eyes, but occurred in 16% of the 0.5-s PRP eyes. There was complete disc neovascular regression in 85% of the 0.1-s PRP eyes and 81% of the 0.5-s PRP eyes. These trends were not statistically significant.
Keywords
Public Health Clinical Trial High Risk Argon Exposure TimePreview
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References
- 1.Blankenship GW (1986) Red krypton and blue-green argon panretinal laser photocoagulation for proliferative diabetic retinopathy: a laboratory and clinical comparison. Trans Am Ophthalmol Soc 84:967–1003Google Scholar
- 2.Blankenship GW (1988) A clinical comparison of central and peripheral argon laser panretinal photocoagulation for proliferative diabetic retinopathy. Ophthalmology 95:170–177Google Scholar
- 3.Diabetic Retinopathy Study Research Group (1976) Preliminary report on effects of photocoagulation therapy. Am J Ophthalmol 81:383–396Google Scholar
- 4.Diabetic Retinopathy Study Research Group (1978) Photocoagulation treatment of proliferative diabetic retinopathy; the second report of the DRS findings. Ophthalmology 85:82–106Google Scholar
- 5.Diabetic Retinopathy Study Research Group (1979) Four risk factors for severe visual loss in diabetic retinopathy: the third report from the DRS. Arch Ophthalmol 97:654–655Google Scholar
- 6.Diabetic Retinopathy Study Research Group (1981) Photocoagulation treatment of proliferative diabetic retinopathy: clinical application of DRS findings, DRS report number 8. Ophthalmology 88:583–600Google Scholar
- 7.Doft BH, Blankenship GW (1982) Single versus multiple treatment sessions of argon laser panretinal photocoagulation for proliferative diabetic retinopathy. Ophthalmology 89:772–779Google Scholar
- 8.Ferris FL, Podgor MJ, Davis MD, Diabetic Retinopathy Study Research Group (1987) Macular edema in diabetic retinopathy study patients. Diabetic Retinopathy Study Report Number 12. Ophthalmology 94:754–760Google Scholar
- 9.Little HL (1983) Proliferative diabetic retinopathy: pathogenesis and treatment. In: Little HL, Jack RL, Patz A, Forsham PH (eds) Diabetic retinopathy. Thieme-Stratton, New York, pp 257–273Google Scholar
- 10.McDonald HR, Schatz H (1985) Visual loss following panretinal photocoagulation for proliferative diabetic retinopathy. Ophthalmology 92:388–393Google Scholar
- 11.McDonald HR, Schatz H (1985) Macular edema following panretinal photocoagulation. Retina 5:5–10Google Scholar
- 12.Meyers SM (1980) Macular edema after scatter laser photocoagulation for proliferative diabetic retinopathy. Am J Ophthalmol 90:519–524Google Scholar
- 13.Molnar J, Poitry S, Tsacopoulos M, Giladi N, Leuenberger PM (1985) Effect of laser photocoagulation on oxygenation of the retina in miniature pigs. Invest Ophthalmol Vis Sci 26:1410–1414Google Scholar
- 14.Stefansson E, Hatchell DL, Fisher BL, Sutherland FS, Machemer R (1986) Panretinal photocoagulation and retinal oxygenation in normal and diabetic cats. Am J Ophthahnol 101:657–664Google Scholar
- 15.Wallow IHL, Davis MD (1979) Clinicopathologic correlation of xenon arc and argon laser photocoagulation: procedure in human diabetic eyes. Arch Ophthalmol 97:2308–2315Google Scholar