Abstract
Pattern reversals with a ramp-like temporal course evoke transient pattern electroretinograms (PERG) that are delayed and attenuated in comparison with responses evoked by a step-like course (abrupt pattern reversals). This delay depends on the reversal time and probably represents a measure for temporal characteristics of the activated retinal structures. A pattern reversal stimulator with adjustable reversa) periods (matrix of 8X14 rectangular red light emitting diodes, element size 2° X 1°, stimulus area 16° X 14°) was used to record transient PERGs from 20 glaucomatous eyes with early or moderate visual field damages (measured with computer perimetry). The q-wave (P1) amplitude difference between the glaucoma group and normal subjects with step-like reversal stimulation was not significantP=0.23). On the other hand, a highly significant separation (P< 0.0001) between both groups was possible using the P1 latency at ramp-like stimulation or the response latency shift between step and ramp-like stimulation (Pattern reversal time, 30 ms).
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Mierdel, P., Zenker, H.J. & Marré, E. The pattern ERG in glaucoma: effect of pattern reversal time. Int Ophthalmol 16, 211–214 (1992). https://doi.org/10.1007/BF00917963
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DOI: https://doi.org/10.1007/BF00917963