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International Ophthalmology

, Volume 16, Issue 1, pp 23–26 | Cite as

Relationship between precorneal retention of viscous eye drops and tear fluid composition

  • A. Ludwig
  • N. J. van Haeringen
  • V. M. W. Bodelier
  • M. Van Ooteghem
Article

Abstract

The influence of viscolysers on the precorneal residence of a fluorescent tracer was determined, using slit lamp fluorophotometry. The solution acceptability was evaluated by the volunteers by answering a standard questionnaire.

The relationship between precorneal retention of viscous eye drops, discomfort and tear fluid composition after instillation of various cellulosic solutions was examined. Irritating hydroxypropylcellulose solution increases the total protein concentration of tears, without change in the ratio of lysozyme to total protein.

Key words

precorneal retention tear fluid composition viscous eye drops 

Abbreviations

HEC

hydroxyethylcellulose

HPC

hydroxypropylcellulose

HPMC

hydroxypropyl-methylcellulose

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Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • A. Ludwig
    • 1
  • N. J. van Haeringen
    • 2
  • V. M. W. Bodelier
    • 2
  • M. Van Ooteghem
    • 1
  1. 1.University of Antwerp (UIA)Belgium
  2. 2.The Netherlands Ophthalmic Research InstituteAmsterdamThe Netherlands

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