Summary
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1.
From compounds of the type CCl2=CH(CH2)nX (X=C6Hg5, C6H4Cl, n=1; X=COOH, n=2, 3, 4, 6; X=C6H4(CO)2N, n=4) the following α-amino carboxylic acids were prepared: 3-phenylalanine, 3-p-chlorophenylalanine, glutamlc, α-aminoadipic, α-aminopimelic, and α-aminosuberlc acids, and lysine dihydrochloride.
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2.
A method is proposed for the synthesis of 2-chloro-3-phenylpropionlc acid by the action of chlorine on 1,1-dichloro-3-phenylpropene in a formic acid medium.
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Freidlina, R.K., Kost, V.N., Vasil'eva, T.T. et al. Synthesis of inactive α-aminocarboxylic acids from compounds containing a CC12=CH group. Russ Chem Bull 8, 800–803 (1959). https://doi.org/10.1007/BF00915906
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DOI: https://doi.org/10.1007/BF00915906