Journal of Abnormal Child Psychology

, Volume 5, Issue 4, pp 405–416 | Cite as

Lead and hyperactivity: Lead levels among hyperactive children

  • Oliver J. David
  • Stanley P. Hoffman
  • Jeffrey Sverd
  • Julian Clark


Previous work has demonstrated an association between hyperactivity and increased body lead burdens in school-age children. In the present study it is shown that within a group of hyperactive children those for whom an organic etiology is present have lead burdens lower than in those for whom no apparent cause could be found. These data lead us to reject the notion that hyperactivity per se is responsible for the acquisition of elevated lead levels, and further strengthen the suspicion that for some children lower lead level absorption may be implicated in the development of the hyperkinetic disorder.


Level Absorption Lead Level Hyperactive Child Hyperkinetic Disorder Lower Lead 
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  1. Baloh, R. W. Laboratory diagnosis of increased lead absorption.Archives of Environmental Health, 1974,28, 198–208.Google Scholar
  2. Byers, R. K., & Lord, E. E. Late effects of lead poisoning on mental development.American Journal of Diseases of Children, 1943,66, 471–494.Google Scholar
  3. Chisholm, J. J., & Harrison, H. E. The exposure of children to lead.Pediatrics, 1956,18, 943–958.Google Scholar
  4. Conners, C. K. A teacher rating scale for use in drug studies with children.American Journal of Psychiatry, 1969,126, 884–888.Google Scholar
  5. David, O., Clark, J., & Voeller, K. Lead and hyperactivity.The Lancet, 1972,2, 900–903.Google Scholar
  6. David, O., Huffman, S. P., Sverd, J., Clark, J., & Voeller, K. Lead and hyperactivity. Behavioral response to chelation: A pilot study.American Journal of Psychaitry, 1976,133, 1155–1158.Google Scholar
  7. Hessel, D. W. A simple and rapid quantitative determination of lead in blood.Atomic Absorption Newsletter, 1968,7, 55–56.Google Scholar
  8. Lansdown, R. G., Shepherd, J., Clayton, B. E., & Delves, H. T. Blood-lead levels, behavior and intelligence: A population study.The Lancet, 1974,1, 538–541.Google Scholar
  9. Lin-Fu, J. Undue absorption of lead among children — a new look at an old problem.New England Journal of Medicine, 1972,286, 702–710.Google Scholar
  10. Minde, K., Webb, G., & Sykes, D. Studies on the hyperactive child VI: Prenatal and paranatal factors associated with hyperactivity.Developmental Medicine and Child Neurology, 1968,10, 355–363.Google Scholar
  11. Mirdal, G. K., Mednick, S. A., Schulsinger, F., & Fuchs, F. Perinatal complications in children of schizophrenic mothers.Acta Psychiatrica Scandinavica, 1974,50, 553–568.Google Scholar
  12. Perlstein, M. A., & Attala, R. Neurologic sequelae of plumbism in children.Clinical Pediatrics, 1966,5, 292–298.Google Scholar
  13. Smith, H. D., Baehner, R. L., Carney, T., & Major, W. J. The sequelae of pica with and without lead poisoning.Americal Journal of Diseases of Children, 1963,105, 609–616.Google Scholar
  14. Thurston, D. L., Middelkamp, J. N., & Mason, E. The late effects of lead poisoning.Journal of Pediatrics, 1955,47, 413–423.Google Scholar
  15. Werry, J. S. Developmental hyperactivity.Pediatric Clinics of North America, 1968,15, 581–599.Google Scholar
  16. Wiener, G. Varying psychological sequelae of lead ingestion in children.Public Health Report, 1970,85, 19–24.Google Scholar
  17. Winer, B. J.Statistical principles in experimental design. New York: McGraw-Hill, 1962.Google Scholar

Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • Oliver J. David
    • 1
  • Stanley P. Hoffman
    • 1
  • Jeffrey Sverd
    • 1
  • Julian Clark
    • 1
  1. 1.Downstate Medical CenterUSA

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